Pre-prints
AJ Lea, IV Caldas, KM Garske, J Echwa, M Gurven, C Handley, J Kahumbu, J Kamau, P Kinyua, F Lotukoi, A Lopurudoi, S Lowasa, R Mallarino, D Martins, PW Messer, C Miano, B Muhoya, J Peng, T Phung, JD Rabinowitz, A Roichman, R Siford, A Stone, AM Taravella-Oill, S Mathew, MA Wilson, JF Ayroles. Adaptations to water stress and pastoralism in the Turkana of northwest Kenya. bioRxiv [link].
AM Arner, B Muhoya, M Sanchez Rozado, M Gurven, J Kahumbu, J Kamau, P Kinyua, F Lotukoi, DJ Martins, C Miano, MJ Montague, SN Njeru, J Peng, P Straub, MM Watowich, LK Davis, N Snyder-Mackler, JF Ayroles, AJ Lea. Exposure to urban environments alters sex differences in immune physiology. bioRxiv [link].
S Rosenbaum, A Malani, AJ Lea, J Tung, SC Alberts, EA Archie. Testing early life effects frameworks: developmental constraints and adaptive response hypotheses do not explain fertility outcomes in female baboons. bioRxiv [link].
RM Petersen, CM Vockley, AJ Lea. Uncovering methylation-dependent genetic effects on regulatory element function in diverse genomes. bioRxiv [link].
MW Watowich, AM Arner, S Wang, E John, JC Kahumbu, P Kinyua, A Lopurudoi, F Lotukoi, CM Mwai, B Muhoya, B Mukoma, KL Tam, TBT A/P Tan Boon Huat, M Gurven, YAL Lim, D Martins, S Njeru, KS Ng, VV Venkataraman, IJ Wallace, JF Ayroles, TS Kraft, AJ Lea. The built environment is more predictive of cardiometabolic health than other aspects of lifestyle in two rapidly transitioning Indigenous populations. medRxiv [link].
AM Arner, B Muhoya, M Sanchez Rozado, M Gurven, J Kahumbu, J Kamau, P Kinyua, F Lotukoi, DJ Martins, C Miano, MJ Montague, SN Njeru, J Peng, P Straub, MM Watowich, LK Davis, N Snyder-Mackler, JF Ayroles, AJ Lea. Exposure to urban environments alters sex differences in immune physiology. bioRxiv [link].
S Rosenbaum, A Malani, AJ Lea, J Tung, SC Alberts, EA Archie. Testing early life effects frameworks: developmental constraints and adaptive response hypotheses do not explain fertility outcomes in female baboons. bioRxiv [link].
RM Petersen, CM Vockley, AJ Lea. Uncovering methylation-dependent genetic effects on regulatory element function in diverse genomes. bioRxiv [link].
MW Watowich, AM Arner, S Wang, E John, JC Kahumbu, P Kinyua, A Lopurudoi, F Lotukoi, CM Mwai, B Muhoya, B Mukoma, KL Tam, TBT A/P Tan Boon Huat, M Gurven, YAL Lim, D Martins, S Njeru, KS Ng, VV Venkataraman, IJ Wallace, JF Ayroles, TS Kraft, AJ Lea. The built environment is more predictive of cardiometabolic health than other aspects of lifestyle in two rapidly transitioning Indigenous populations. medRxiv [link].
Publications
2024
SK Patterson, E Andonov, AM Arre, MI Martínez, JE Negron-Del Valle, RM Petersen, D Phillips, A Rahman, A Ruiz-Lambides, I Villanueva, AJ Lea, N Snyder-Mackler, LJN Brent, JP Higham. 2024. Early life adversity has sex-dependent effects on survival across the lifespan in rhesus macaques. Philosophical Transactions B, accepted.
M Gurven, A Sarieddine, AJ Lea. 2024. Health disparities among Indigenous peoples: exploring the roles of evolutionary and developmental mismatch on cardiometabolic health. Annual Review of Anthropology, accepted.
AW Reynolds, AJ Lea, MA Nieves-Colón. 2024. Genomics research in lower- and middle-income countries: ethics, common challenges, and emerging solutions. In: M Moller, G Patrinos, C Uren, eds. Population Genomics in the Developing World. Elsevier Academic Press.
L Brassington*, A Arner*, M Watowich, J Damstedt, N Kee Seong, YAL Lim, VV Venkataraman, I Wallace, TS Kraft, AJ Lea. 2024. Integrating the Thrifty Genotype and Evolutionary Mismatch Hypotheses to understand variation in cardiometabolic disease risk. Evolution, Medicine, and Public Health, eoae014 [link].
M Watowich, C Costa, K Chiou, E Goldman, R Petersen, S Patterson, M Martinez, K Sterner, J Horvath, M Montague, M Platt, L Brent, J Higham, AJ Lea*, N Snyder-Mackler*. 2024. Immune gene regulation is associated with age and environmental adversity in a nonhuman primate. Molecular Ecology, doi.10.1111/mec.17445 [link].
RM Petersen, AJ Lea. 2024. Preview: Diet composition impacts eQTL discovery across multiple tissues in baboons. Cell Genomics, 4:100524 [link].
RA Johnston, KA Aracena, LB Barreiro, AJ Lea, J Tung. 2024. DNA methylation-environment interactions in the human genome. eLife, doi.org/10.7554/eLife.89371.2 [link].
JA Anderson, D Lin, AJ Lea, RA Johnston, T Voyles, MY Akinyi, E Archie, SC Alberts, J Tung. 2024. DNA methylation signatures of early life adversity are exposure-dependent in wild baboons. Proceedings of the National Academy of Sciences, 121:e2309469121 [link].
KP Pettie, M Mumbach, AJ Lea, JF Ayroles, HY Chang, M Kasowski, HB Fraser. 2024. Chromatin activity identifies differential gene regulation across human ancestries. Genome Biology, 25:21 [link].
2023
AJ Lea, AG Clark, AW Dahl, O Devinsky, AR Garcia, CD Golden, J Kamau, TS Kraft, YAL Lim, D Martins, D Mogoi, P Pajukanta, G Perry, H Pontzer, BC Trumble, SS Urlacher, VV Venkataraman, IJ Wallace, M Gurven, D Lieberman, JF Ayroles. 2023. Applying an evolutionary mismatch framework to understand disease susceptibility. PLoS Biology, 21: e3002311 [link].
MM Watowich, KL Chiou, B Graves, MJ Montague, LJN Brent, JP Higham, JE Horvath, Amy Lu, MI Martinez, ML Platt, IA Schneider-Crease, AJ Lea, N Snyder-Mackler. 2023. Best practices for genotype imputation from low-coverage sequencing data in natural populations. Molecular Ecology Resources, online early [link].
SK Patterson, RM Petersen, LJN Brent, N Snyder-Mackler, AJ Lea, JP Higham. 2023. Natural animal populations as models for understanding early life adversity effects on aging. Integrative and Comparative Biology, 63:681-692 [link].
S Peterson, M Watowich, L Renner, S Martin, E Offenberg, AJ Lea, M Montague, J Higham, N Snyder-Mackler, M Neuringer, B Ferguson. 2023. Genetic variants in melanogenesis proteins TYRP1 and TYR are associated with the golden rhesus macaque phenotype. G3: Genes, Genomes, Genetics, online early [link].
S Wolf, D Melo, KM Garske, LF Pallares, AJ Lea, JF Ayroles. 2023. Characterizing the landscape of gene expression variance in humans. PLoS Genetics, 19:e1010833 [link].
BC Trumble, M Charifson, T Kraft, AR Garcia, DK Cummings, P Hooper, AJ Lea, D Eid Rodriguez, SV Koebele, K Buetow, B Beheim, R Minocher, M Gutierrez, GS Thomas, M Gatz, J Stieglitz, CE Finch, H Kaplan, M Gurven. 2023. Apolipoprotein E4 is associated with higher fecundity in a natural fertility population. Science Advances, 9:eade9797 [link].
I Gallego Romero*, AJ Lea*. 2023. Leveraging massively parallel reporter assays for evolutionary questions. Genome Biology, 24:26 [link].
AJ Lea, A Garcia, J Arevalo, JF Ayroles, K Buetow, SW Cole, D Eid Rodriguez, M Gutierrez, HM Highland, A Justice, T Kraft, KE North, J Stieglitz, H Kaplan, BC Trumble, MD Gurven. 2023. Natural selection of immune and metabolic genes associated with health in South American Amerindians. Proceedings of the National Academy of Sciences, 120:e2207544120 [link].
2022
LP Pallares*, AJ Lea*, C Han, EV Filippova, P Andolfatto, JF Ayroles. 2022. Dietary stress remodels the genetic architecture of lifespan variation in outbred Drosophila. Nature Genetics, 55:123-129 [link]
AJ Lea, J Peng, JF Ayroles. 2022. Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects on gene expression levels. Genome Research, 32:1-14 [link].
IJ Wallace, AJ Lea, YAL Lim, SKW Chow, I bin Mohd Sayed, R Ngui, MTH Shaffee, KS Ng, C Nicholas, VV Venkataraman, TS Kraft. 2022. Orang Asli Health and Lifeways Project (OA HeLP): Study Protocol. BMJ Open, 12:e058660 [link].
J Anderson, AJ Lea, T Voyles, M Akinyi, R Nyakundi, L Ochola, M Omondi, F Nyundo, Y Zhang, FA Campos, SC Alberts, EA Archie, J Tung. 2022. Distinct gene regulatory signatures of dominance rank and social bond strength in wild baboons. Philosophical Transactions of the Royal Society B, 377: 20200441 [link].
2018-2021
AJ Lea, C Waigwa, B Muhoya, F Lotukoi, J Peng, LP Henry, V Abhyankar, J Kamau, D Martins, M Gurven, JF Ayroles. 2021. Social gradients in health vary between rural and urban Turkana. Evolution, Medicine, and Public Health, 9:406-419 [link].
CSC Johnson, CA Shively, KT Michalson, AJ Lea, RJ DeBo, TD Howard, GA Hawkins, SE Appt, Y Liu, CE McCall, D Herrington, TC Register*, N Snyder-Mackler*. 2021. Divergent effects of Western and Mediterranean diets on behavior and monocyte polarization. eLife, 10:e68293 [link].
JA Anderson*, RA Johnston*, AJ Lea, FA Campos, TN Voyles, MY Akinyi, SC Alberts, EA Archie, J Tung. 2021. High social status males experience accelerated epigenetic aging in wild baboons. eLife, 10:e66128 [link].
AJ Lea, D Martins, J Kamau, M Gurven, JF Ayroles. 2020. Urbanization and market-integration have strong, non-linear effects on cardiometabolic health in the Turkana. Science Advances, 6:eabb1430 [link].
AJ Lea*, S Rosebaum*. Understanding how early life effects evolve: progress, gaps, and future directions. 2020. Current Opinion in Behavioral Sciences, 36:29-35 [link].
AJ Lea*, M Subramaniam*, A Ko, T Lehtimäki, E Raitoharju, M Kähönen, I Seppälä, N Mononen, OT Raitakari, M Ala-Korpela, P Pajukanta, NA Zaitlen, JF Ayroles. 2019. Genetic and environmental perturbations lead to regulatory decoherence. eLife, 8:e40538 [link].
AJ Lea, CM Vockley, RA Johnston, CA Del Carpio, LB Barreiro, TE Reddy, J Tung. 2018. Genome-wide quantification of the effects of DNA methylation on human gene regulation. eLife, 7:e37513 [link].
AJ Lea, MY Akinyi, R Nyakundi, P Mareri, F Nyundo, T Kariuki, SC Alberts, EA Archie, J Tung. 2018. Dominance rank-associated immune gene expression is widespread, sex-specific, and a precursor to high social status in wild male baboons. Proceedings of the National Academy of Sciences, 115:E12163-E12171 [link].
N Snyder-Mackler*, AJ Lea*. 2018. Functional genomic insights into the environmental determinants of mammalian fitness. Current Opinion in Genetics and Development, 53:105-112 [link].
AJ Lea, J Tung, EA Archie, SC Alberts. 2018. Developmental plasticity: bridging research in evolution and human health. Evolution, Medicine, and Public Health, 1:162-175 [link].
*See also: AJ Lea, J Tung, EA Archie, SC Alberts. 2018. Developmental plasticity research in evolution and human health: response to commentaries. Evolution, Medicine, and Public Health, 1:201-205 [link].
LEK Serieys, AJ Lea, M Epeldegui, TC Armenta, J Moriarty, S VandeWoude, S Carver, J Foley, RK Wayne, SPD Riley, CH Uittenbogaart. 2018. Urbanization and anticoagulant poisons promote immune dysfunction in bobcats. Proceedings of the Royal Society Series B, 285:20172533 [link].
2012-2017
AJ Lea, PAP Durst, TP Vilgalys, J Tung. 2017. Maximizing ecological and evolutionary insight from bisulfite sequencing data sets. Nature Ecology and Evolution, 1:1074-1083 [link].
P Charruau, R Johnston, DR Stahler, AJ Lea, N Snyder-Mackler, DW Smith, B vonHoldt, SW Cole, J Tung, RK Wayne. 2016. Pervasive effects of aging on gene expression in wild wolves. Molecular Biology and Evolution 33:1967-1978 [link].
AJ Lea, J Altmann, SC Alberts, J Tung. 2016. Resource base influences genome-wide DNA methylation levels in wild baboons. Molecular Ecology 25:1681-1696 [link].
AJ Lea, J Tung, X Zhou. 2015. A flexible, efficient binomial mixed model for identifying differential DNA methylation in bisulfite sequencing data. PLoS Genetics 11:e1005650 [link].
KP Koepfli, J Pollinger, R Godinho, J Robinson, AJ Lea, S Hendricks, RM Schweizer, O Thalmann, P Silva, Z Fan, AA Yurchenko, P Dobrynin, A Makunin, JA Cahill, B Shapiro, F Alvares, JC Brito, E Geffen, JA Leonard, KM Helgen, WE Johnson, SJ O'Brien, B Van Valkenburgh, RK Wayne. 2015. Genome-wide evidence reveals that African golden jackals are a distinct species. Current Biology 25:2158–2165 [link].
AJ Lea, J Altmann, SC Alberts, J Tung. 2015. Developmental constraints in a wild primate. The American Naturalist 185: 809-821 [link].
LEK Serieys, AJ Lea, J Pollinger, SPD Riley, RK Wayne. 2014. Disease and freeways drive genetic change in urban bobcat populations. Evolutionary Applications 8:75-92 [link].
AJ Lea, NH Learm, MJ Theus, J Altmann, SC Alberts. 2014. Complex sources of variance in female dominance rank in a nepotistic society. Animal Behaviour 94:87-99 [link].
DM Shier, AJ Lea, MA Owen. 2012. Beyond masking: Endangered Stephen's kangaroo rats respond to traffic noise with footdrumming. Biological Conservation 150:53-58 [link].
Before 2012
AJ Lea and DT Blumstein. 2011. Ontogenetic and sex differences influence alarm call responses in mammals: a meta-analysis. Ethology 117:839-851 [PDF].
AJ Lea and DT Blumstein. 2011. Age and sex influence marmot antipredator behavior during periods of heightened risk. Behavioral Ecology and Sociobiology 65:1525-1533 [PDF].
AJ Lea, DT Blumstein, TW Wey, JGA Martin. 2010. Heritable victimization and the benefits of agonistic relationships. Proceedings of the National Academy of Sciences 107:21587-21592 [PDF].
DT Blumstein, AJ Lea, LE Olson, JGA Martin. 2010. Heritability of anti-predator traits: vigilance and locomotor performance in marmots. Journal of Evolutionary Biology 23:879-887 [PDF].
AJ Lea, JP Barrera, LM Tom, DT Blumstein. 2008. Heterospecific eavesdropping in a nonsocial species. Behavioral Ecology 19:1041-1046 [PDF].
SK Patterson, E Andonov, AM Arre, MI Martínez, JE Negron-Del Valle, RM Petersen, D Phillips, A Rahman, A Ruiz-Lambides, I Villanueva, AJ Lea, N Snyder-Mackler, LJN Brent, JP Higham. 2024. Early life adversity has sex-dependent effects on survival across the lifespan in rhesus macaques. Philosophical Transactions B, accepted.
M Gurven, A Sarieddine, AJ Lea. 2024. Health disparities among Indigenous peoples: exploring the roles of evolutionary and developmental mismatch on cardiometabolic health. Annual Review of Anthropology, accepted.
AW Reynolds, AJ Lea, MA Nieves-Colón. 2024. Genomics research in lower- and middle-income countries: ethics, common challenges, and emerging solutions. In: M Moller, G Patrinos, C Uren, eds. Population Genomics in the Developing World. Elsevier Academic Press.
L Brassington*, A Arner*, M Watowich, J Damstedt, N Kee Seong, YAL Lim, VV Venkataraman, I Wallace, TS Kraft, AJ Lea. 2024. Integrating the Thrifty Genotype and Evolutionary Mismatch Hypotheses to understand variation in cardiometabolic disease risk. Evolution, Medicine, and Public Health, eoae014 [link].
M Watowich, C Costa, K Chiou, E Goldman, R Petersen, S Patterson, M Martinez, K Sterner, J Horvath, M Montague, M Platt, L Brent, J Higham, AJ Lea*, N Snyder-Mackler*. 2024. Immune gene regulation is associated with age and environmental adversity in a nonhuman primate. Molecular Ecology, doi.10.1111/mec.17445 [link].
RM Petersen, AJ Lea. 2024. Preview: Diet composition impacts eQTL discovery across multiple tissues in baboons. Cell Genomics, 4:100524 [link].
RA Johnston, KA Aracena, LB Barreiro, AJ Lea, J Tung. 2024. DNA methylation-environment interactions in the human genome. eLife, doi.org/10.7554/eLife.89371.2 [link].
JA Anderson, D Lin, AJ Lea, RA Johnston, T Voyles, MY Akinyi, E Archie, SC Alberts, J Tung. 2024. DNA methylation signatures of early life adversity are exposure-dependent in wild baboons. Proceedings of the National Academy of Sciences, 121:e2309469121 [link].
KP Pettie, M Mumbach, AJ Lea, JF Ayroles, HY Chang, M Kasowski, HB Fraser. 2024. Chromatin activity identifies differential gene regulation across human ancestries. Genome Biology, 25:21 [link].
2023
AJ Lea, AG Clark, AW Dahl, O Devinsky, AR Garcia, CD Golden, J Kamau, TS Kraft, YAL Lim, D Martins, D Mogoi, P Pajukanta, G Perry, H Pontzer, BC Trumble, SS Urlacher, VV Venkataraman, IJ Wallace, M Gurven, D Lieberman, JF Ayroles. 2023. Applying an evolutionary mismatch framework to understand disease susceptibility. PLoS Biology, 21: e3002311 [link].
MM Watowich, KL Chiou, B Graves, MJ Montague, LJN Brent, JP Higham, JE Horvath, Amy Lu, MI Martinez, ML Platt, IA Schneider-Crease, AJ Lea, N Snyder-Mackler. 2023. Best practices for genotype imputation from low-coverage sequencing data in natural populations. Molecular Ecology Resources, online early [link].
SK Patterson, RM Petersen, LJN Brent, N Snyder-Mackler, AJ Lea, JP Higham. 2023. Natural animal populations as models for understanding early life adversity effects on aging. Integrative and Comparative Biology, 63:681-692 [link].
S Peterson, M Watowich, L Renner, S Martin, E Offenberg, AJ Lea, M Montague, J Higham, N Snyder-Mackler, M Neuringer, B Ferguson. 2023. Genetic variants in melanogenesis proteins TYRP1 and TYR are associated with the golden rhesus macaque phenotype. G3: Genes, Genomes, Genetics, online early [link].
S Wolf, D Melo, KM Garske, LF Pallares, AJ Lea, JF Ayroles. 2023. Characterizing the landscape of gene expression variance in humans. PLoS Genetics, 19:e1010833 [link].
BC Trumble, M Charifson, T Kraft, AR Garcia, DK Cummings, P Hooper, AJ Lea, D Eid Rodriguez, SV Koebele, K Buetow, B Beheim, R Minocher, M Gutierrez, GS Thomas, M Gatz, J Stieglitz, CE Finch, H Kaplan, M Gurven. 2023. Apolipoprotein E4 is associated with higher fecundity in a natural fertility population. Science Advances, 9:eade9797 [link].
I Gallego Romero*, AJ Lea*. 2023. Leveraging massively parallel reporter assays for evolutionary questions. Genome Biology, 24:26 [link].
AJ Lea, A Garcia, J Arevalo, JF Ayroles, K Buetow, SW Cole, D Eid Rodriguez, M Gutierrez, HM Highland, A Justice, T Kraft, KE North, J Stieglitz, H Kaplan, BC Trumble, MD Gurven. 2023. Natural selection of immune and metabolic genes associated with health in South American Amerindians. Proceedings of the National Academy of Sciences, 120:e2207544120 [link].
2022
LP Pallares*, AJ Lea*, C Han, EV Filippova, P Andolfatto, JF Ayroles. 2022. Dietary stress remodels the genetic architecture of lifespan variation in outbred Drosophila. Nature Genetics, 55:123-129 [link]
AJ Lea, J Peng, JF Ayroles. 2022. Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects on gene expression levels. Genome Research, 32:1-14 [link].
IJ Wallace, AJ Lea, YAL Lim, SKW Chow, I bin Mohd Sayed, R Ngui, MTH Shaffee, KS Ng, C Nicholas, VV Venkataraman, TS Kraft. 2022. Orang Asli Health and Lifeways Project (OA HeLP): Study Protocol. BMJ Open, 12:e058660 [link].
J Anderson, AJ Lea, T Voyles, M Akinyi, R Nyakundi, L Ochola, M Omondi, F Nyundo, Y Zhang, FA Campos, SC Alberts, EA Archie, J Tung. 2022. Distinct gene regulatory signatures of dominance rank and social bond strength in wild baboons. Philosophical Transactions of the Royal Society B, 377: 20200441 [link].
2018-2021
AJ Lea, C Waigwa, B Muhoya, F Lotukoi, J Peng, LP Henry, V Abhyankar, J Kamau, D Martins, M Gurven, JF Ayroles. 2021. Social gradients in health vary between rural and urban Turkana. Evolution, Medicine, and Public Health, 9:406-419 [link].
CSC Johnson, CA Shively, KT Michalson, AJ Lea, RJ DeBo, TD Howard, GA Hawkins, SE Appt, Y Liu, CE McCall, D Herrington, TC Register*, N Snyder-Mackler*. 2021. Divergent effects of Western and Mediterranean diets on behavior and monocyte polarization. eLife, 10:e68293 [link].
JA Anderson*, RA Johnston*, AJ Lea, FA Campos, TN Voyles, MY Akinyi, SC Alberts, EA Archie, J Tung. 2021. High social status males experience accelerated epigenetic aging in wild baboons. eLife, 10:e66128 [link].
AJ Lea, D Martins, J Kamau, M Gurven, JF Ayroles. 2020. Urbanization and market-integration have strong, non-linear effects on cardiometabolic health in the Turkana. Science Advances, 6:eabb1430 [link].
AJ Lea*, S Rosebaum*. Understanding how early life effects evolve: progress, gaps, and future directions. 2020. Current Opinion in Behavioral Sciences, 36:29-35 [link].
AJ Lea*, M Subramaniam*, A Ko, T Lehtimäki, E Raitoharju, M Kähönen, I Seppälä, N Mononen, OT Raitakari, M Ala-Korpela, P Pajukanta, NA Zaitlen, JF Ayroles. 2019. Genetic and environmental perturbations lead to regulatory decoherence. eLife, 8:e40538 [link].
AJ Lea, CM Vockley, RA Johnston, CA Del Carpio, LB Barreiro, TE Reddy, J Tung. 2018. Genome-wide quantification of the effects of DNA methylation on human gene regulation. eLife, 7:e37513 [link].
AJ Lea, MY Akinyi, R Nyakundi, P Mareri, F Nyundo, T Kariuki, SC Alberts, EA Archie, J Tung. 2018. Dominance rank-associated immune gene expression is widespread, sex-specific, and a precursor to high social status in wild male baboons. Proceedings of the National Academy of Sciences, 115:E12163-E12171 [link].
N Snyder-Mackler*, AJ Lea*. 2018. Functional genomic insights into the environmental determinants of mammalian fitness. Current Opinion in Genetics and Development, 53:105-112 [link].
AJ Lea, J Tung, EA Archie, SC Alberts. 2018. Developmental plasticity: bridging research in evolution and human health. Evolution, Medicine, and Public Health, 1:162-175 [link].
*See also: AJ Lea, J Tung, EA Archie, SC Alberts. 2018. Developmental plasticity research in evolution and human health: response to commentaries. Evolution, Medicine, and Public Health, 1:201-205 [link].
LEK Serieys, AJ Lea, M Epeldegui, TC Armenta, J Moriarty, S VandeWoude, S Carver, J Foley, RK Wayne, SPD Riley, CH Uittenbogaart. 2018. Urbanization and anticoagulant poisons promote immune dysfunction in bobcats. Proceedings of the Royal Society Series B, 285:20172533 [link].
2012-2017
AJ Lea, PAP Durst, TP Vilgalys, J Tung. 2017. Maximizing ecological and evolutionary insight from bisulfite sequencing data sets. Nature Ecology and Evolution, 1:1074-1083 [link].
P Charruau, R Johnston, DR Stahler, AJ Lea, N Snyder-Mackler, DW Smith, B vonHoldt, SW Cole, J Tung, RK Wayne. 2016. Pervasive effects of aging on gene expression in wild wolves. Molecular Biology and Evolution 33:1967-1978 [link].
AJ Lea, J Altmann, SC Alberts, J Tung. 2016. Resource base influences genome-wide DNA methylation levels in wild baboons. Molecular Ecology 25:1681-1696 [link].
AJ Lea, J Tung, X Zhou. 2015. A flexible, efficient binomial mixed model for identifying differential DNA methylation in bisulfite sequencing data. PLoS Genetics 11:e1005650 [link].
KP Koepfli, J Pollinger, R Godinho, J Robinson, AJ Lea, S Hendricks, RM Schweizer, O Thalmann, P Silva, Z Fan, AA Yurchenko, P Dobrynin, A Makunin, JA Cahill, B Shapiro, F Alvares, JC Brito, E Geffen, JA Leonard, KM Helgen, WE Johnson, SJ O'Brien, B Van Valkenburgh, RK Wayne. 2015. Genome-wide evidence reveals that African golden jackals are a distinct species. Current Biology 25:2158–2165 [link].
AJ Lea, J Altmann, SC Alberts, J Tung. 2015. Developmental constraints in a wild primate. The American Naturalist 185: 809-821 [link].
LEK Serieys, AJ Lea, J Pollinger, SPD Riley, RK Wayne. 2014. Disease and freeways drive genetic change in urban bobcat populations. Evolutionary Applications 8:75-92 [link].
AJ Lea, NH Learm, MJ Theus, J Altmann, SC Alberts. 2014. Complex sources of variance in female dominance rank in a nepotistic society. Animal Behaviour 94:87-99 [link].
DM Shier, AJ Lea, MA Owen. 2012. Beyond masking: Endangered Stephen's kangaroo rats respond to traffic noise with footdrumming. Biological Conservation 150:53-58 [link].
Before 2012
AJ Lea and DT Blumstein. 2011. Ontogenetic and sex differences influence alarm call responses in mammals: a meta-analysis. Ethology 117:839-851 [PDF].
AJ Lea and DT Blumstein. 2011. Age and sex influence marmot antipredator behavior during periods of heightened risk. Behavioral Ecology and Sociobiology 65:1525-1533 [PDF].
AJ Lea, DT Blumstein, TW Wey, JGA Martin. 2010. Heritable victimization and the benefits of agonistic relationships. Proceedings of the National Academy of Sciences 107:21587-21592 [PDF].
DT Blumstein, AJ Lea, LE Olson, JGA Martin. 2010. Heritability of anti-predator traits: vigilance and locomotor performance in marmots. Journal of Evolutionary Biology 23:879-887 [PDF].
AJ Lea, JP Barrera, LM Tom, DT Blumstein. 2008. Heterospecific eavesdropping in a nonsocial species. Behavioral Ecology 19:1041-1046 [PDF].